PDB entry 4wwk

View 4wwk on RCSB PDB site
Description: Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting molecule CD1d, and Beta-2-microglobulin
Class: immune system
Keywords: Innate Immunity, NKT, IMMUNE SYSTEM
Deposited on 2014-11-11, released 2016-02-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TCR Alpha Chain-TRAV12-3
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4WWK
    Domains in SCOPe 2.07: d4wwka1, d4wwka2
  • Chain 'B':
    Compound: TCR Beta Chain-TRBV6-5
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4WWK (Start-242)
    Domains in SCOPe 2.07: d4wwkb1, d4wwkb2
  • Chain 'C':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4wwkc1, d4wwkc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4wwkd_
  • Heterogens: NAG, JLS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4wwkA (A:)
    mqkeveqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedg
    rftaqvdksskyislfirdsqpsdsatylcamsgdlntnagkstfgdgttltvkpniqnp
    dpavyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavaw
    snksdfacanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wwkA (A:)
    eqdpgplsvpegaivslnctysnsafqyfmwyrqysrkgpellmytyssgnkedgrftaq
    vdksskyislfirdsqpsdsatylcamsgdlntnagkstfgdgttltvkpniqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
    facanafn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4wwkB (B:)
    mnagvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqge
    vpngynvsrsttedfplrllsaapsqtsvyfcassqgpfqpqhfgdgtrlsiledlknvf
    ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
    alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
    rad
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wwkB (B:)
    gvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgevpn
    gynvsrsttedfplrllsaapsqtsvyfcassqgpfqpqhfgdgtrlsiledlknvfppe
    vavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpaln
    dsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgrad
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4wwkC (C:)
    spgvpqrlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfs
    dqqwetlqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafq
    gkdilsfqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgks
    elkkqvkpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpna
    detwylratldvvageaaglscrvkhsslegqdivlyw
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wwkC (C:)
    fplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwetlq
    hifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdilsfq
    gtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqvkp
    kawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwylra
    tldvvageaaglscrvkhsslegqdivlyw
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4wwkD (D:)
    msrsvalavlallslsgleaiqrtpkiqvysrhpaengksnflncyvsgfhpsdievdll
    kngeriekvehsdlsfskdwsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wwkD (D:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm