PDB entry 4wux

View 4wux on RCSB PDB site
Description: Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D) Complexed with Mannose
Class: sugar binding protein
Keywords: collectin, carbohydrate binding, lectin, lipid binding, sugar binding protein
Deposited on 2014-11-03, released 2016-02-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-02-10, with a file datestamp of 2016-02-05.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pulmonary surfactant-associated protein A
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Sftpa1, Sftp-1, Sftp1, Sftpa
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08427 (Start-147)
      • engineered mutation (90)
      • engineered mutation (94)
      • engineered mutation (106)
      • engineered mutation (122)
    Domains in SCOPe 2.06: d4wuxa1, d4wuxa2
  • Heterogens: MAN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4wuxA (A:)
    ayldeelqtelyeikhqilqtmgvlslqgsmlsvgdkvfstngqsvnfdtikemctragg
    niavprtpeeneaiasiakkynnyvylgmiddqtegdfhyldgasvsytnwypgeprgqg
    kedcvemytdgtwndrgclqyrlavcef
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wuxA (A:)
    lqtelyeikhqilqtmgvlslqgsmlsvgdkvfstngqsvnfdtikemctraggniavpr
    tpeeneaiasiakkynnyvylgmiddqtegdfhyldgasvsytnwypgeprgqgkedcve
    mytdgtwndrgclqyrlavcef