PDB entry 4wur

View 4wur on RCSB PDB site
Description: The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin
Class: hydrolase
Keywords: MERS-CoV, Papain-like protease, Ubiquitin, Complex, hydrolase
Deposited on 2014-11-03, released 2014-11-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-09-28, with a file datestamp of 2016-09-23.
Experiment type: XRAY
Resolution: 3.16 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: papain-like protease
    Species: Betacoronavirus England 1 [TaxId:1263720]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot K9N7C7
      • conflict (97)
      • engineered mutation (116)
      • conflict (241)
    Domains in SCOPe 2.08: d4wura1, d4wura2
  • Chain 'B':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4wurb_
  • Heterogens: IPA, ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wurA (A:)
gshmasqltievlvtvdgvnfrtvvlnnkntyrsqlgcvffngadisdtipdekqnghsl
yladnltadetkalkelygpvdptflhrfyslkaavhgwkmvvcdkvrslklsdnnsyln
avimtldllkdikfvipalqhafmkhkggdstdfialimaygnctfgapddasrllhtvl
akaelccsarmvwrewcnvcgikdvvlqglkaccyvgvqtvedlrarmtyvcqcggerhr
qlvehttpwlllsgtpneklvttstapdfvafnvfqgietavghyvharlkgglilkfds
gtvsktsdwkckvtdvlfpgqkyssd

    Sequence, based on observed residues (ATOM records): (download) 
    >4wurA (A:)
tievlvtvdgvnfrtvvlnnkntyrsqlgcvffngadisdtipdekqnghslyladnlta
detkalkelygpvdptflhrfyslkaavhgwkmvvcdkvrslklsdnnsylnavimtldl
lkdikfvipalqhafmkhkggdstdfialimaygnctfgapddasrllhtvlakaelccs
armvwrewcnvcgikdvvlqglkaccyvgvqtvedlrarmtyvcqcggerhrqlvehttp
wlllsgtpneklvttstapdfvafnvfqgietavghyvharlkgglilkfdsgtvsktsd
wkckvtdvlfpgqkyss

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4wurB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >4wurB (B:)
ifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyniq
kestlhlvlrlrgg