PDB entry 4ws7

View 4ws7 on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 5-chlorouracil, Form II
Class: hydrolase
Keywords: DNA-repair, Excision repair, Conformational selection, Ligand-binding, HYDROLASE
Deposited on 2014-10-25, released 2015-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.88 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: uracil-DNA glycosylase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: ung, Rv2976c, MTCY349.11
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4ws7a_
  • Heterogens: 5UC, CL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4ws7A (A:)
    mhhhhhhgmasmtarplselvergwaaalepvadqvahmgqflraeiaagrrylpagsnv
    lraftfpfdnvrvlivgqdpyptpghavglsfsvapdvrpwprslanifdeytadlgypl
    psngdltpwaqrgvlllnrvltvrpsnpashrgkgweavtecairalaaraaplvailwg
    rdastlkpmlaagncvaiesphpsplsasrgffgsrpfsranellvgmgaepidwrlp
    

    Sequence, based on observed residues (ATOM records): (download)
    >4ws7A (A:)
    rplselvergwaaalepvadqvahmgqflraeiaagrrylpagsnvlraftfpfdnvrvl
    ivgqdpyptpghavglsfsvapdvrpwprslanifdeytadlgyplpsngdltpwaqrgv
    lllnrvltvrpsnpashrgkgweavtecairalaaraaplvailwgrdastlkpmlaagn
    cvaiesphpsplsasrgffgsrpfsranellvgmgaepidwrlp