PDB entry 4wrg

View 4wrg on RCSB PDB site
Description: 1.9 angstrom structure of EGFR kinase domain
Class: transferase
Keywords: transferase, kinase domain
Deposited on 2014-10-23, released 2014-11-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-11-05, with a file datestamp of 2014-10-31.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.198
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epidermal growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EGFR, ERBB, ERBB1, HER1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00533 (3-End)
      • expression tag (1-2)
    Domains in SCOPe 2.08: d4wrga1, d4wrga2
  • Heterogens: NA, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wrgA (A:)
gamgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreats
pkankeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsq
yllnwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhae
ggkvpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekger
lpqppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsp
tdsnfyralmdeedmddvvdadeylipqqg

    Sequence, based on observed residues (ATOM records): (download) 
    >4wrgA (A:)
amgeapnqallrilketefkkikvlgtvykglwipegekvkipvaikespknkeildeay
vmasvdnphvcrllgicltsvqlitqlmpfgclldyvrehkdnigsqyllnwcvqiakgm
nyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaekvpikwmalesil
hriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymim
vkcwmidadsrpkfreliiefskmardpqrylviqgdmddvvdadeylip