PDB entry 4wo4

View 4wo4 on RCSB PDB site
Description: The molecular bases of Delta/Alpha beta T cell-mediated antigen recognition.
Class: immune system
Keywords: Immunity, IMMUNE SYSTEM
Deposited on 2014-10-15, released 2014-11-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Antigen-presenting glycoprotein CD1d
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1D
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15813 (Start-271)
      • expression tag (272-273)
    Domains in SCOPe 2.07: d4wo4a1, d4wo4a2, d4wo4a3
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4wo4b_
  • Chain 'C':
    Compound: TCR variable DELTA 1 CHAIN and TCR constant Alpha
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4WO4
    Domains in SCOPe 2.07: d4wo4c1, d4wo4c2
  • Chain 'D':
    Compound: TCR variable BETA 2 (TRVB20) chain and TCR constant BETA
    Species: Homo sapiens [TaxId:9606]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4WO4
    Domains in SCOPe 2.07: d4wo4d1, d4wo4d2
  • Heterogens: NAG, BMA, FUC, JLS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4wo4A (A:)
    rlfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwet
    lqhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdils
    fqgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqv
    kpkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwyl
    ratldvvageaaglscrvkhsslegqdivlywpr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wo4A (A:)
    lfplrclqissfansswtrtdglawlgelqthswsndsdtvrslkpwsqgtfsdqqwetl
    qhifrvyrssftrdvkefakmlrlsyplelqvsagcevhpgnasnnffhvafqgkdilsf
    qgtsweptqeaplwvnlaiqvlnqdkwtretvqwllngtcpqfvsgllesgkselkkqvk
    pkawlsrgpspgpgrlllvchvsgfypkpvwvkwmrgeqeqqgtqpgdilpnadetwylr
    atldvvageaaglscrvkhsslegqdivlywpr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4wo4B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wo4B (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4wo4C (C:)
    hmaqkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqna
    ksgrysvnfkkaaksvaltisalqledsakyfcalgvtgkltfgqgtiltvhpniqnpdp
    avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
    ksdfacanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wo4C (C:)
    qkvtqaqssvsmpvrkavtlnclyetswwsyyifwykqlpskemiflirqgsdeqnaksg
    rysvnfkkaaksvaltisalqledsakyfcalgvtgkltfgqgtiltvhpniqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
    facanafnnsiipedtffps
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4wo4D (D:)
    hmgavvsqhpsrvisksgtsvkiecrsldfqattmfwyrqfpkqslmlmatsnegskaty
    eqgvekdkflinhasltlstltvtsahpedssfyicsapggvgaffgqgtrltvvedlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >4wo4D (D:)
    gavvsqhpsrvisksgtsvkiecrsldfqattmfwyrqfpkqslmlmatsnegskatyeq
    gvekdkflinhasltlstltvtsahpedssfyicsapggvgaffgqgtrltvvedlknvf
    ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
    alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
    ra