PDB entry 4wn5

View 4wn5 on RCSB PDB site
Description: Crystal structure of the C-terminal Per-Arnt-Sim (PASb) of human HIF-3alpha9 bound to 18:1-1-monoacylglycerol
Class: transcription
Keywords: HIF-3alpha, PAS domain, monoacylglycerol, lipid, fatty acid, TRANSCRIPTION
Deposited on 2014-10-10, released 2015-08-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-08-05, with a file datestamp of 2015-07-31.
Experiment type: XRAY
Resolution: 1.15 Å
R-factor: N/A
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hypoxia-inducible factor 3-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: HIF3A, BHLHE17, MOP7, PASD7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y2N7 (4-End)
      • expression tag (2-3)
    Domains in SCOPe 2.06: d4wn5a1, d4wn5a2
  • Chain 'B':
    Compound: Hypoxia-inducible factor 3-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: HIF3A, BHLHE17, MOP7, PASD7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4wn5b_
  • Heterogens: SO4, MVC, P6G, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wn5A (A:)
gshmgrgaflsrhsldmkftycddriaevagyspddligcsayeyihaldsdavsksiht
llskgqavtgqyrflarsggylwtqtqatvvsggrgpqsesivcvhflisqveet

    Sequence, based on observed residues (ATOM records): (download) 
    >4wn5A (A:)
hmgrgaflsrhsldmkftycddriaevagyspddligcsayeyihaldsdavsksihtll
skgqavtgqyrflarsggylwtqtqatvvsgrgpqsesivcvhflisq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4wn5B (B:)
gshmgrgaflsrhsldmkftycddriaevagyspddligcsayeyihaldsdavsksiht
llskgqavtgqyrflarsggylwtqtqatvvsggrgpqsesivcvhflisqveet

    Sequence, based on observed residues (ATOM records): (download) 
    >4wn5B (B:)
rgaflsrhsldmkftycddriaevagyspddligcsayeyihaldsdavsksihtllskg
qavtgqyrflarsggylwtqtqatvvsggrgpqsesivcvhflis