PDB entry 4wi2
View 4wi2 on RCSB PDB site
Description: Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc (wild-type)
Class: immune system
Keywords: Human IgG1, FcRn binding site, Therapeutic antibody, IMMUNE SYSTEM
Deposited on
2014-09-25, released
2015-09-30
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-09-13, with a file datestamp of
2017-09-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ig gamma-1 chain C region
Species: Homo sapiens [TaxId:9606]
Gene: IGHG1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4wi2a1, d4wi2a2 - Chain 'B':
Compound: Ig gamma-1 chain C region
Species: Homo sapiens [TaxId:9606]
Gene: IGHG1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4wi2b1, d4wi2b2 - Heterogens: NAG, BMA, MAN, FUC, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4wi2A (A:)
gpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeqy
nstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsrd
eltknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflyskltvdksr
wqqgnvfscsvmhealhnhytqkslsls
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4wi2B (B:)
gpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeqy
nstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsrd
eltknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflyskltvdksr
wqqgnvfscsvmhealhnhytqkslsls