PDB entry 4wf2

View 4wf2 on RCSB PDB site
Description: Structure of E. coli BirA G142A bound to biotinol-5'-AMP
Class: ligase
Keywords: biotin protein ligase, biotin repressor, G142A mutant, complex with biotinol-5'-AMP, LIGASE
Deposited on 2014-09-11, released 2014-10-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional ligase/repressor BirA
    Species: Escherichia coli [TaxId:83333]
    Gene: birA, bioR, dhbB, b3973, JW3941
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06709
      • engineered mutation (141)
    Domains in SCOPe 2.08: d4wf2a1, d4wf2a2, d4wf2a3
  • Heterogens: BTX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wf2A (A:)
mkdntvplkliallangefhsgeqlgetlgmsraainkhiqtlrdwgvdvftvpgkgysl
pepiqllnakqilgqldggsvavlpvidstnqylldrigelksgdaciaeyqqagrgrrg
rkwfspfganlylsmfwrleqapaaaiglslvigivmaevlrklgadkvrvkwpndlylq
drklagilveltgktgdaaqivigaginmamrrveesvvnqgwitlqeaginldrntlaa
mlirelraalelfeqeglapylsrwekldnfinrpvkliigdkeifgisrgidkqgalll
eqdgiikpwmggeislrsaekhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4wf2A (A:)
dntvplkliallangefhsgeqlgetlgmsraainkhiqtlrdwgvdvftvpgkgyslpe
piqllnakqilgqldggsvavlpvidstnqylldrigelksgdaciaeyqqagrgrrgrk
wfspfganlylsmfwrleqapaaaiglslvigivmaevlrklgadkvrvkwpndlylqdr
klagilveltdaaqivigaginmamgwitlqeaginldrntlaamlirelraalelfeqe
glapylsrwekldnfinrpvkliigdkeifgisrgidkqgallleqdgiikpwmggeisl
rsae