PDB entry 4wex

View 4wex on RCSB PDB site
Description: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation Y168S
Class: hydrolase
Keywords: hydrolase, myelin, nervous system
Deposited on 2014-09-11, released 2015-09-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2',3'-cyclic-nucleotide 3'-phosphodiesterase
    Species: Mus musculus [TaxId:10090]
    Gene: Cnp, Cnp1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16330 (Start-220)
      • engineered mutation (10)
    Domains in SCOPe 2.07: d4wexa_
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wexA (A:)
gglekdflplsfgwfltkkssetlrkagqvfleelgnhkafkkelrhfisgdepkeklel
vsyfgkrppgvlhcttkfcdygkaagaeeyaqqevvkrsygkafklsisalfvtpktaga
qvvltdqelqlwpsdldkpsaseglppgsrahvtlgcaadvqpvqtgldlldilqqvkgg
sqgeavgelprgklyslgkgrwmlsltkkmevkaiftgyyg

    Sequence, based on observed residues (ATOM records): (download) 
    >4wexA (A:)
lekdflplsfgwfltkkssetlrkagqvfleelgnhkafkkelrhfkeklelvsyfgkrp
pgvlhcttkfcdygkaagaeeyaqqevvkrsygkafklsisalfvtpktagaqvvltdqe
lqlwpsdldkpsaseglppgsrahvtlgcaadvqpvqtgldlldilqqvkggsqgeavge
lprgklyslgkgrwmlsltkkmevkaiftgyyg