PDB entry 4w7h

View 4w7h on RCSB PDB site
Description: Crystal Structure of DEH Reductase A1-R Mutant
Class: oxidoreductase
Keywords: ALPHA/BETA/ALPHA, ROSSMANN-FOLD, Alginate metabolism, Short-chain dehydrogenase/reductase, OXIDOREDUCTASE, loop-exchange
Deposited on 2014-08-22, released 2014-09-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-29, with a file datestamp of 2020-01-24.
Experiment type: XRAY
Resolution: 3.11 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: carbonyl reductase
    Species: Sphingomonas sp. A1 [TaxId:90322]
    Gene: a1-R
    Database cross-references and differences (RAF-indexed):
    • Uniprot D6RU56 (0-257)
      • engineered mutation (15-16)
      • engineered mutation (36-40)
    Domains in SCOPe 2.08: d4w7ha_
  • Chain 'B':
    Compound: carbonyl reductase
    Species: Sphingomonas sp. A1 [TaxId:90322]
    Gene: a1-R
    Database cross-references and differences (RAF-indexed):
    • Uniprot D6RU56 (0-257)
      • engineered mutation (15-16)
      • engineered mutation (36-40)
    Domains in SCOPe 2.08: d4w7hb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4w7hA (A:)
mfpdlkgkrvlitgstegiglatarlfaragakvglnshvdpanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashla
sgyitgqvldinggqykh

    Sequence, based on observed residues (ATOM records): (download) 
    >4w7hA (A:)
mfpdlkgkrvlitgstegiglatarlfaragakvglnshvdpanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtvddvrdrisngipmgrfgtaeemapaflffashlasgyitgqvl
dinggqykh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4w7hB (B:)
mfpdlkgkrvlitgstegiglatarlfaragakvglnshvdpanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtvdtafhadktqdvrdrisngipmgrfgtaeemapaflffashla
sgyitgqvldinggqykh

    Sequence, based on observed residues (ATOM records): (download) 
    >4w7hB (B:)
mfpdlkgkrvlitgstegiglatarlfaragakvglnshvdpanidetiasmradggdaa
ffaadlatseacqqlvdefvakfggidvlinnagglvgrkplpeiddtfydavmdanirs
vvmttkfalphlaaaakasgqtsavistgsiaghtgggpgaglygaakaflhnvhknwvd
fhtkdgvrfnivspgtisngipmgrfgtaeemapaflffashlasgyitgqvldinggqy
kh