PDB entry 4w4w

View 4w4w on RCSB PDB site
Description: JNK2/3 in complex with N-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}benzamide
Class: transferase/transferase inhibitor
Keywords: JNK, MAP kinase, isoform selective, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2014-08-15, released 2015-02-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: c-Jun N-terminal kinase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK10, JNK3, JNK3A, PRKM10, SAPK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4w4wa_
  • Heterogens: 3HJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4w4wA (A:)
mamskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikkls
rpfqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqv
iqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagt
sfmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvi
eqlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardll
skmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliyk
evmnse

    Sequence, based on observed residues (ATOM records): (download) 
    >4w4wA (A:)
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartasfmmtpyvvt
ryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpef
mkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpak
risvddalqhpyinvwydpaeveapppqlderehtieewkeliykevmn