PDB entry 4uyd

View 4uyd on RCSB PDB site
Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1,3-dimethyl-2-oxo-2,3- dihydro-1H-1,3-benzodiazole-5-carboxamide
Class: transcription
Keywords: transcription, inhibitor, histone, epigenetic reader, antagonist
Deposited on 2014-08-30, released 2014-09-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-03, with a file datestamp of 2014-11-28.
Experiment type: XRAY
Resolution: 1.37 Å
R-factor: 0.17483
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (13-End)
      • expression tag (12)
    Domains in SCOPe 2.08: d4uyda1, d4uyda2
  • Heterogens: DMS, EDO, V1T, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uydA (A:)
gsshhhhhhssgmnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdav
klnlpdyykiiktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlma
ealeklflqkinelpteeteimivqakgrgrgr

    Sequence, based on observed residues (ATOM records): (download) 
    >4uydA (A:)
mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
elpteet