SCOPe 2.08: Structural Classification of Proteins

PDB entry 4uwp

View 4uwp on RCSB PDB site
Description: Penta Zn1 coordination. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding.
Class: hydrolase
Keywords: hydrolase, antibiotic resistance, drug binding site
Deposited on 2014-08-14, released 2015-02-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

Chain 'B':
Compound: metallo-beta-lactamase vim-26
Species: Klebsiella pneumoniae [TaxId:573]
Database cross-references and differences (RAF-indexed):
- Uniprot E5BDC6 (0-End)
Domains in SCOPe 2.08: d4uwpb_
Heterogens: ZN, HOH

PDB Chain Sequences:

Chain 'B':
Sequence, based on SEQRES records: (download)

>4uwpB (B:)
eyptvneipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaeaegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsanvlyggcavlelsstsagnv
adadlaewptsveriqkhypeaevvipghglpggldllqhtanvvkahknrsvae

Sequence, based on observed residues (ATOM records): (download)

>4uwpB (B:)
eyptvneipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaeaegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsanvlyggcavlelsstsagnv
adadlaewptsveriqkhypeaevvipghglpggldllqhtanvvkahkn