PDB entry 4uwo

View 4uwo on RCSB PDB site
Description: Native di-zinc VIM-26. Leu224 in VIM-26 from Klebsiella pneumoniae has implications for drug binding.
Class: hydrolase
Keywords: hydrolase, antibiotic resistance, klebsiella pneumoniae, drug binding site
Deposited on 2014-08-14, released 2015-02-04
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-04-15, with a file datestamp of 2015-04-10.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: metallo-beta-lactamase vim-26
    Species: Klebsiella pneumoniae [TaxId:573]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4uwob_
  • Heterogens: NA, ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4uwoB (B:)
mlkvissllvymtasvmavasplahsgepsgeyptvneipvgevrlyqiadgvwshiatq
sfdgavypsnglivrdgdelllidtawgakntaallaeiekqiglpvtravsthfhddrv
ggvdvlraagvatyaspstrrlaeaegneipthsleglsssgdavrfgpvelfypgaahs
tdnlvvyvpsanvlyggcavlelsstsagnvadadlaewptsveriqkhypeaevvipgh
glpggldllqhtanvvkahknrsvae

    Sequence, based on observed residues (ATOM records): (download) 
    >4uwoB (B:)
eyptvneipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaeaegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsanvlyggcavlelsstsagnv
adadlaewptsveriqkhypeaevvipghglpggldllqhtanvvkahkn