PDB entry 4uwj

View 4uwj on RCSB PDB site
Description: Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a capped pyrazole sulphonamide ligand
Class: transferase
Keywords: transferase, drug discovery
Deposited on 2014-08-12, released 2014-12-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-14, with a file datestamp of 2018-02-09.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycylpeptide N-tetradecanoyltransferase
    Species: Aspergillus fumigatus [TaxId:746128]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4uwja1, d4uwja2
  • Heterogens: 7L5, MYA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4uwjA (A:)
    qtqpvprfdetstdtggpikiidpekvskepdallegfewatldltnetelqelwdllty
    hyveddnamfrfrysqsflhwalmspgwkkewhvgvratksrklvasicgvpteinvrnq
    klkvveinflcihkklrskrltpvlikeitrrcylngiyqaiytagvvlptpvsscryyh
    rpldwlklyevgfsplpagstkarqitknhlpsttstpglrpmepkdidtvhdllqryls
    rfalnqaftreevdhwlvhkpetvkeqvvwayvvedpethkitdffsfynlestviqnpk
    hdnvraaylyyyatetaftnnmkalkerllmlmndalilakkahfdvfnaltlhdnplfl
    eqlkfgagdgqlhfylynyrtapvpggvneknlpdekrmggvgivml
    

    Sequence, based on observed residues (ATOM records): (download)
    >4uwjA (A:)
    ggpikiidpekvskepdallegfewatldltnetelqelwdlltyhyveddnamfrfrys
    qsflhwalmspgwkkewhvgvratksrklvasicgvpteinvrnqklkvveinflcihkk
    lrskrltpvlikeitrrcylngiyqaiytagvvlptpvsscryyhrpldwlklyevgfsp
    lpagstkarqitknhlpsttstpglrpmepkdidtvhdllqrylsrfalnqaftreevdh
    wlvhkpetvkeqvvwayvvedpethkitdffsfynlestviqnpkhdnvraaylyyyate
    taftnnmkalkerllmlmndalilakkahfdvfnaltlhdnplfleqlkfgagdgqlhfy
    lynyrtapvpggvneknlpdekrmggvgivml