PDB entry 4uwi

View 4uwi on RCSB PDB site
Description: Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a pyrazole sulphonamide ligand
Class: transferase
Keywords: transferase, drug discovery
Deposited on 2014-08-12, released 2014-12-03
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-01-14, with a file datestamp of 2015-01-09.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.179
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycylpeptide N-tetradecanoyltransferase
    Species: Aspergillus fumigatus [TaxId:746128]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4uwia1, d4uwia2
  • Heterogens: XMQ, MYA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uwiA (A:)
qtqpvprfdetstdtggpikiidpekvskepdallegfewatldltnetelqelwdllty
hyveddnamfrfrysqsflhwalmspgwkkewhvgvratksrklvasicgvpteinvrnq
klkvveinflcihkklrskrltpvlikeitrrcylngiyqaiytagvvlptpvsscryyh
rpldwlklyevgfsplpagstkarqitknhlpsttstpglrpmepkdidtvhdllqryls
rfalnqaftreevdhwlvhkpetvkeqvvwayvvedpethkitdffsfynlestviqnpk
hdnvraaylyyyatetaftnnmkalkerllmlmndalilakkahfdvfnaltlhdnplfl
eqlkfgagdgqlhfylynyrtapvpggvneknlpdekrmggvgivml

    Sequence, based on observed residues (ATOM records): (download) 
    >4uwiA (A:)
ggpikiidpekvskepdallegfewatldltnetelqelwdlltyhyveddnamfrfrys
qsflhwalmspgwkkewhvgvratksrklvasicgvpteinvrnqklkvveinflcihkk
lrskrltpvlikeitrrcylngiyqaiytagvvlptpvsscryyhrpldwlklyevgfsp
lpagstkarqitknhlpsttstpglrpmepkdidtvhdllqrylsrfalnqaftreevdh
wlvhkpevkeqvvwayvvedpethkitdffsfynlestviqnpkhdnvraaylyyyatet
aftnnmkalkerllmlmndalilakkahfdvfnaltlhdnplfleqlkfgagdgqlhfyl
ynyrtapvpggvneknlpdekrmggvgivml