PDB entry 4uuq

View 4uuq on RCSB PDB site
Description: Crystal structure of human mono-glyceride lipase in complex with SAR127303
Class: hydrolase
Keywords: hydrolase
Deposited on 2014-07-30, released 2015-01-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 2.36 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Monoglyceride lipase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4uuqa_
  • Chain 'B':
    Compound: Monoglyceride lipase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4uuqb_
  • Heterogens: 64D, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uuqA (A:)
mhhhhhhmetgpedpssmpeessprrtpqsipyqdlphlvnadgqylfcrywkptgtpka
lifvshgagehsgryeelarmlmgldllvfahdhvghgqsegermvvsdfhvfvrdvlqh
vdsmqkdypglpvfllghsmggaiailtaaerpghfagmvlisplvlanpesattfkvla
akvlnlvlpnlslgpidssvlsrnktevdiynsdplicraglkvcfgiqllnavsrvera
lpkltvpflllqgsadrlcdskgayllmelaksqdktlkiyegayhvlhkelpevtnsvf
heinmwvsqrtatagtaspp

    Sequence, based on observed residues (ATOM records): (download) 
    >4uuqA (A:)
sprrtpqsipyqdlphlvnadgqylfcrywkptgtpkalifvshgagehsgryeelarml
mgldllvfahdhvghgqsegermvvsdfhvfvrdvlqhvdsmqkdypglpvfllghsmgg
aiailtaaerpghfagmvlisplvlanpesattfkvlaakvlnlvlpnlslgpidssvls
rnktevdiynsdplicraglkvcfgiqllnavsrveralpkltvpflllqgsadrlcdsk
gayllmelaksqdktlkiyegayhvlhkelpevtnsvfheinmwvsqrta

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4uuqB (B:)
mhhhhhhmetgpedpssmpeessprrtpqsipyqdlphlvnadgqylfcrywkptgtpka
lifvshgagehsgryeelarmlmgldllvfahdhvghgqsegermvvsdfhvfvrdvlqh
vdsmqkdypglpvfllghsmggaiailtaaerpghfagmvlisplvlanpesattfkvla
akvlnlvlpnlslgpidssvlsrnktevdiynsdplicraglkvcfgiqllnavsrvera
lpkltvpflllqgsadrlcdskgayllmelaksqdktlkiyegayhvlhkelpevtnsvf
heinmwvsqrtatagtaspp

    Sequence, based on observed residues (ATOM records): (download) 
    >4uuqB (B:)
dlphlvnadgqylfcrywkptgtpkalifvshgagehsgryeelarmlmgldllvfahdh
vghgqsegermvvsdfhvfvrdvlqhvdsmqkdypglpvfllghsmggaiailtaaerpg
hfagmvlisplvlanpesattfkvlaakvlnlvlpnlslgpidssvlsrnktevdiynsd
plicraglkvcfgiqllnavsrveralpkltvpflllqgsadrlcdskgayllmelaksq
dktlkiyegayhvlhkelpevtnsvfheinmwvsqrta