PDB entry 4us1

View 4us1 on RCSB PDB site
Description: The crystal structure of H-Ras and SOS in complex with ligands
Class: signaling protein
Keywords: signaling protein
Deposited on 2014-07-02, released 2015-03-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-03-25, with a file datestamp of 2015-03-20.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'R':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (19-184)
      • expression tag (18)
    Domains in SCOPe 2.07: d4us1r1, d4us1r2
  • Chain 'S':
    Compound: Son of sevenless homolog 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4us1s_
  • Heterogens: L71, HOH

PDB Chain Sequences:

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >4us1R (R:)
mhhhhhhgggenlyfqgshmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyr
kqvvidgetclldildtagqeeysamrdqymrtgegflcvfainntksfedihqyreqik
rvkdsddvpmvlvgnkcdlaartvesrqaqdlarsygipyietsaktrqgvedafytlvr
eirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >4us1R (R:)
hmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >4us1S (S:)
meeqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpn
fvrtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyi
qpvqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkki
ardngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqps
elvgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvf
qelnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsi
nppcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclr
vesdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrp
snprpgt

    Sequence, based on observed residues (ATOM records): (download) 
    >4us1S (S:)
eqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfv
rtflttyrsfckpqellsliierfeipepelsaelkrfrkeyiqpvqlrvlnvcrhwveh
hfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiafqsspptvewhisrpg
hietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkeinspnllkmirhtt
nltlwfekcivetenleervavvsriieilqvfqelnnfngvlevvsamnsspvyrldht
feqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltnilkteegnpevlk
rhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmgnsmekeftdyl
fnksleieprnpkplprfpkkysyplkspgvrpsnp