PDB entry 4uio

View 4uio on RCSB PDB site
Description: Structure of the Salmonella typhi Type I Dehydroquinase covalently inhibited by a 3-dehydroquinic acid derivative
Class: lyase
Keywords: bacterial proteins, binding sites, crystallization, lyase, inhibitor, protein binding, shikimis acid pathway, substrate specificity
Deposited on 2015-03-30, released 2015-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-08-29, with a file datestamp of 2018-08-24.
Experiment type: XRAY
Resolution: 1.35 Å
R-factor: N/A
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-dehydroquinate dehydratase
    Species: Salmonella enterica subsp. enterica serovar Typhi [TaxId:90370]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4uioa_
  • Heterogens: VAU, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uioA (A:)
mktvtvknliigegmpkiivslmgrdinsvkaealayreatfdilewrvdhfmdiastqs
vltaarvirdampdipllftfrsakeggeqtittqhyltlnraaidsglvdmidlelftg
dadvkatvdyahahnvyvvmsnhdfhqtpsaeemvlrlrkmqalgadipkiavmpqskhd
vltlltatlemqqhyadrpvitmsmakegvisrlagevfgsaatfgavkqasapgqiavn
dlrsvlmilhna

    Sequence, based on observed residues (ATOM records): (download) 
    >4uioA (A:)
tvtvknliigegmpkiivslmgrdinsvkaealayreatfdilewrvdhfmdiastqsvl
taarvirdampdipllftfrsakeggeqtittqhyltlnraaidsglvdmidlelftgda
dvkatvdyahahnvyvvmsnhdfhqtpsaeemvlrlrkmqalgadipkiavmpqskhdvl
tlltatlemqqhyadrpvitmsmakegvisrlagevfgsaatfgavkqasapgqiavndl
rsvlmilhna