PDB entry 4uia

View 4uia on RCSB PDB site
Description: Crystal structure of 3a in complex with tafCPB
Class: hydrolase
Keywords: hydrolase, tafi, carboxypeptidase, thrombosis, fibrinolysis, drug discovery
Deposited on 2015-03-27, released 2015-06-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-08-26, with a file datestamp of 2015-08-21.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: carboxypeptidase b
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09955 (Start-305)
      • expression tag (306)
      • engineered mutation (64)
      • engineered mutation (191)
      • engineered mutation (198)
      • engineered mutation (200)
      • engineered mutation (244)
      • engineered mutation (246)
      • engineered mutation (248)
      • engineered mutation (251)
    Domains in SCOPe 2.08: d4uiaa1, d4uiaa2
  • Heterogens: ZN, FH9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4uiaA (A:)
ttghsyekynnwetieawtkqvtsenpdlisrtaigttflgnniyllkvgkpgpnkpaif
mdcgiharewishafcqwfvreavltygyeshmteflnkldfyvlpvlnidgyiytwtkn
rmwrktrstnagttcigtdpnrnfdagwcttgastdpcdetycgsaaeseketkaladfi
rnnlssikaylsihsysqhivypysydyklpennaelnnlakaavkelatlygtkytygp
gattlylapgggddwaydqgikysftfelrdkgrygfilpesqiqatceetmlaikyvtn
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    Sequence, based on observed residues (ATOM records): (download) 
    >4uiaA (A:)
ghsyekynnwetieawtkqvtsenpdlisrtaigttflgnniyllkvgkpgpnkpaifmd
cgiharewishafcqwfvreavltygyeshmteflnkldfyvlpvlnidgyiytwtknrm
wrktrstnagttcigtdpnrnfdagwcttgastdpcdetycgsaaeseketkaladfirn
nlssikaylsihsysqhivypysydyklpennaelnnlakaavkelatlygtkytygpga
ttlylapgggddwaydqgikysftfelrdkgrygfilpesqiqatceetmlaikyvtnyv
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