PDB entry 4ui2
View 4ui2 on RCSB PDB site
Description: Crystal structure of the ternary RGMB-BMP2-NEO1 complex
Class: signaling protein
Keywords: repulsive guidance molecule, bone morphogenetic protein pathway, hemojuvelin, morphogen, axon guidance, cell surface receptor signaling, neogenin, signaling protein
Deposited on
2015-03-27, released
2015-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-07-29, with a file datestamp of
2020-06-29.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: N/A
AEROSPACI score: 0.18
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Neogenin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: bone morphogenetic protein 2, bmp2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4ui2b_ - Chain 'C':
Compound: repulsive guidance molecule c, rgmc, hemojuvelin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: repulsive guidance molecule c, rgmc, hemojuvelin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: SRT, ACT
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4ui2B (B:)
qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
Sequence, based on observed residues (ATOM records): (download)
>4ui2B (B:)
kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.