PDB entry 4u8z

View 4u8z on RCSB PDB site
Description: Crystal structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06447475)
Class: transferase/transferase inhibitor
Keywords: MST3, pyrrolopyrimidine, inhibitor, kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2014-08-05, released 2015-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-03-18, with a file datestamp of 2015-03-13.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase 24
    Species: Homo sapiens [TaxId:9606]
    Gene: STK24, MST3, STK3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4u8za_
  • Heterogens: MN, 3FE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4u8zA (A:)
glpgmqnlkadpeelftklekigkgsfgevfkgidnrtqkvvaikiidleeaedeiediq
qeitvlsqcdspyvtkyygsylkdtklwiimeylgggsaldllepgpldetqiatilrei
lkgldylhsekkihrdikaanvllsehgevkladfgvagqltdtqikrntfvgtpfwmap
evikqsaydskadiwslgitaielargepphselhpmkvlflipknnpptlegnyskplk
efveaclnkepsfrptakellkhkfilrnakktsyltelidrykrwkaeq