PDB entry 4u2m

View 4u2m on RCSB PDB site
Description: Crystal structure of a complex of the Miz1- and BCL6 POZ domains.
Class: transcription
Keywords: POZ domain, BTB domain, transcription
Deposited on 2014-07-17, released 2014-12-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-12-17, with a file datestamp of 2014-12-12.
Experiment type: XRAY
Resolution: 2.23 Å
R-factor: 0.213
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Zinc finger and BTB domain-containing protein 17,B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13105 (5-118)
      • linker (129-130)
    • Uniprot P41182 (131-End)
    Domains in SCOPe 2.05: d4u2ma1, d4u2ma2
  • Chain 'B':
    Compound: Zinc finger and BTB domain-containing protein 17,B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13105 (5-118)
      • expression tag (2-4)
      • linker (129-130)
    • Uniprot P41182 (131-End)
    Domains in SCOPe 2.05: d4u2mb1, d4u2mb2
  • Chain 'C':
    Compound: Zinc finger and BTB domain-containing protein 17,B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13105 (5-118)
      • expression tag (4)
      • linker (129-130)
    • Uniprot P41182 (131-End)
    Domains in SCOPe 2.05: d4u2mc1, d4u2mc2
  • Chain 'D':
    Compound: Zinc finger and BTB domain-containing protein 17,B-cell lymphoma 6 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL6, BCL5, LAZ3, ZBTB27, ZNF51
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13105 (5-118)
      • expression tag (4)
      • linker (129-130)
    • Uniprot P41182 (131-End)
    Domains in SCOPe 2.05: d4u2md1, d4u2md2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4u2mA (A:)
gplgsdfpqhsqhvleqlnqqrqlgllcdctfvvdgvhfkahkavlaacseyfkmlfvdq
kdvvhldisnaaglgqvlefmytaklslspenvddvlavatflqmqdiitachalkslar
sgggssggsgtadsciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmac
sglfysiftdqlkcnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylq
mehvvdtcrkfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >4u2mA (A:)
dfpqhsqhvleqlnqqrqlgllcdctfvgvhfkahkavlaacseyfkmlfvdqnaaglgq
vlefmytaklslspenvddvlavatflqmqdiitachalkslagtadsciqftrhasdvl
lnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinldpein
pegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfika

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4u2mB (B:)
gplgsdfpqhsqhvleqlnqqrqlgllcdctfvvdgvhfkahkavlaacseyfkmlfvdq
kdvvhldisnaaglgqvlefmytaklslspenvddvlavatflqmqdiitachalkslar
sgggssggsgtadsciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmac
sglfysiftdqlkcnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylq
mehvvdtcrkfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >4u2mB (B:)
lgsdfpqhsqhvleqlnqqrqlgllcdctfvvdgvhfkahkavlaacseyfkmlfvdqkv
hldisnaaglgqvlefmytaklslspenvddvlavatflqmqdiitachalkslagtads
ciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkc
nlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfika

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4u2mC (C:)
gplgsdfpqhsqhvleqlnqqrqlgllcdctfvvdgvhfkahkavlaacseyfkmlfvdq
kdvvhldisnaaglgqvlefmytaklslspenvddvlavatflqmqdiitachalkslar
sgggssggsgtadsciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmac
sglfysiftdqlkcnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylq
mehvvdtcrkfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >4u2mC (C:)
sdfpqhsqhvleqlnqqrqlgllcdctfvvdgvhfkahkavlaacseyfkmlfvddisna
aglgqvlefmytaklslspenvddvlavatflqmqdiitachalkslagtadsciqftrh
asdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkcnlsvinl
dpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfika

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4u2mD (D:)
gplgsdfpqhsqhvleqlnqqrqlgllcdctfvvdgvhfkahkavlaacseyfkmlfvdq
kdvvhldisnaaglgqvlefmytaklslspenvddvlavatflqmqdiitachalkslar
sgggssggsgtadsciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmac
sglfysiftdqlkcnlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylq
mehvvdtcrkfikase

    Sequence, based on observed residues (ATOM records): (download) 
    >4u2mD (D:)
sdfpqhsqhvleqlnqqrqlgllcdctfvvdgvhfkahkavlaacseyfkmlfvdqkdvv
hldisnaaglgqvlefmytaklslspenvddvlavatflqmqdiitachalkslagtads
ciqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdqlkc
nlsvinldpeinpegfcilldfmytsrlnlregnimavmatamylqmehvvdtcrkfika