PDB entry 4txc

View 4txc on RCSB PDB site
Description: Crystal Structure of DAPK1 kinase domain in complex with a small molecule inhibitor
Class: transferase
Keywords: protein-ligand complex, kinase, small-molecule, catalytic domain, protein kinase, protein binding, protein kinase inhibitors, transferase
Deposited on 2014-07-03, released 2014-07-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Death-associated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: DAPK1, DAPK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4txca_
  • Heterogens: 38G, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4txcA (A:)
gsshhhhhhssglvprgshmtvfrqenvddyydtgeelgsgqfavvkkcrekstglqyaa
kfikkrrtkssrrgvsredierevsilkeiqhpnvitlhevyenktdvililelvaggel
fdflaekeslteeeateflkqilngvyylhslqiahfdlkpenimlldrnvpkprikiid
fglahkidfgnefknifgtpefvapeivnyeplgleadmwsigvityillsgaspflgdt
kqetlanvsavnyefedeyfsntsalakdfirrllvkdpkkrmtiqdslqhpwikpkdtq
qals

    Sequence, based on observed residues (ATOM records): (download) 
    >4txcA (A:)
tvfrqenvddyydtgeelgsgqfavvkkcrekstglqyaakfikkrrtkssrrgvsredi
erevsilkeiqhpnvitlhevyenktdvililelvaggelfdflaekeslteeeateflk
qilngvyylhslqiahfdlkpenimlldrnvpkprikiidfglahkidfgnefknifgtp
efvapeivnyeplgleadmwsigvityillsgaspflgdtkqetlanvsavnyefedeyf
sntsalakdfirrllvkdpkkrmtiqdslqhpwikp