PDB entry 4tww
View 4tww on RCSB PDB site
Description: Structure of SARS-3CL protease complex with a Bromobenzoyl (S,R)-N-decalin type inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: hydrase proteinase converting, designed inhibitor, hydrase-inhibitor complex, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2014-07-02, released
2015-02-18
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-02-18, with a file datestamp of
2015-02-13.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: 0.233
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 3C-like proteinase
Species: Human SARS coronavirus [TaxId:227859]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4twwa_ - Chain 'B':
Compound: 3C-like proteinase
Species: Human SARS coronavirus [TaxId:227859]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d4twwb_ - Heterogens: 3A7, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4twwA (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdiqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtfq
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4twwB (B:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdiqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtfq