PDB entry 4tw8

View 4tw8 on RCSB PDB site
Description: The Fk1-Fk2 domains of FKBP52 in complex with iFit-FL
Class: isomerase
Keywords: Fk-506 binding domain, Hsp90 cochaperone, immunophiline, peptidyl-prolyl isomerase, ligand selectivity, isomerase
Deposited on 2014-06-30, released 2014-11-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-24, with a file datestamp of 2014-12-19.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.212
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptidyl-prolyl cis-trans isomerase FKBP4
    Species: Homo sapiens [TaxId:9606]
    Gene: FKBP4, FKBP52
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4tw8a1, d4tw8a2
  • Chain 'B':
    Compound: Peptidyl-prolyl cis-trans isomerase FKBP4
    Species: Homo sapiens [TaxId:9606]
    Gene: FKBP4, FKBP52
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4tw8b1, d4tw8b2
  • Heterogens: 37M, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4tw8A (A:)
egvdispkqdegvlkvikregtgtempmigdrvfvhytgwlldgtkfdssldrkdkfsfd
lgkgevikawdiaiatmkvgevchitckpeyaygsagsppkippnatlvfevelfefkge
dlteeedggiirriqtrgegyakpnegaivevalegyykdklfdqrelrfeigegenldl
pygleraiqrmekgehsivylkpsyafgsvgkekfqippnaelkyelhlksfeka

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4tw8B (B:)
egvdispkqdegvlkvikregtgtempmigdrvfvhytgwlldgtkfdssldrkdkfsfd
lgkgevikawdiaiatmkvgevchitckpeyaygsagsppkippnatlvfevelfefkge
dlteeedggiirriqtrgegyakpnegaivevalegyykdklfdqrelrfeigegenldl
pygleraiqrmekgehsivylkpsyafgsvgkekfqippnaelkyelhlksfeka