PDB entry 4tu1

View 4tu1 on RCSB PDB site
Description: Structure of Toxoplasma gondii fructose 1,6 bisphosphate aldolase
Class: lyase
Keywords: aldolase, F16BP, invasion, toxoplasma, glideosome, Structural Genomics, PSI-2, Protein Structure Initiative, Seattle Structural Genomics Center for Infectious Disease, SSGCID, LYASE
Deposited on 2014-06-23, released 2014-09-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fructose-1,6-bisphosphate aldolase
    Species: Toxoplasma gondii [TaxId:5811]
    Gene: TGVEG_236040
    Database cross-references and differences (RAF-indexed):
    • Uniprot B9PW35 (22-354)
      • expression tag (14-21)
    Domains in SCOPe 2.07: d4tu1a1, d4tu1a2
  • Chain 'B':
    Compound: fructose-1,6-bisphosphate aldolase
    Species: Toxoplasma gondii [TaxId:5811]
    Gene: TGVEG_236040
    Database cross-references and differences (RAF-indexed):
    • Uniprot B9PW35 (22-354)
      • expression tag (15-21)
    Domains in SCOPe 2.07: d4tu1b1, d4tu1b2
  • Chain 'C':
    Compound: fructose-1,6-bisphosphate aldolase
    Species: Toxoplasma gondii [TaxId:5811]
    Gene: TGVEG_236040
    Database cross-references and differences (RAF-indexed):
    • Uniprot B9PW35 (22-354)
      • expression tag (15-21)
    Domains in SCOPe 2.07: d4tu1c1, d4tu1c2
  • Chain 'D':
    Compound: fructose-1,6-bisphosphate aldolase
    Species: Toxoplasma gondii [TaxId:5811]
    Gene: TGVEG_236040
    Database cross-references and differences (RAF-indexed):
    • Uniprot B9PW35 (22-354)
      • expression tag (16-21)
    Domains in SCOPe 2.07: d4tu1d1, d4tu1d2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4tu1A (A:)
mahhhhhhmgtleaqtqgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfd
sigventeanrafyrdllfstkglgqyisgailfeetlyqkspsgvpmvdllkaegiipg
ikvdkgletlpltddekatmgldglserckkyyeagarfakwravlsidpakgkptnlsi
tevahglaryaaicqanrlvpivepeiltdgshditvcaevtervlaavfkalndhhvll
egallkpnmvthgsdcpkpasheeiafytvrslkrtvppalpgvmflsggqseedaslnl
nemnkmgphpfqlsfsygralqasclkawkgvpenkakaqqvlmerarangeaql

    Sequence, based on observed residues (ATOM records): (download) 
    >4tu1A (A:)
qtqgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfdsigventeanrafy
rdllfstkglgqyisgailfeetlyqkspsgvpmvdllkaegiipgikvdkgletlpltd
dekatmgldglserckkyyeagarfakwravlsidpakgkptnlsitevahglaryaaic
qanrlvpivepeiltdgshditvcaevtervlaavfkalndhhvllegallkpnmvthgs
dcpkpasheeiafytvrslkrtvppalpgvmflsggqseedaslnlnemnkmgphpfqls
fsygralqasclkawkgvpenkakaqqvlmerarangeaql

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4tu1B (B:)
mahhhhhhmgtleaqtqgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfd
sigventeanrafyrdllfstkglgqyisgailfeetlyqkspsgvpmvdllkaegiipg
ikvdkgletlpltddekatmgldglserckkyyeagarfakwravlsidpakgkptnlsi
tevahglaryaaicqanrlvpivepeiltdgshditvcaevtervlaavfkalndhhvll
egallkpnmvthgsdcpkpasheeiafytvrslkrtvppalpgvmflsggqseedaslnl
nemnkmgphpfqlsfsygralqasclkawkgvpenkakaqqvlmerarangeaql

    Sequence, based on observed residues (ATOM records): (download) 
    >4tu1B (B:)
tqgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfdsigventeanrafyr
dllfstkglgqyisgailfeetlyqkspsgvpmvdllkaegiipgikvdkgletlpltdd
ekatmgldglserckkyyeagarfakwravlsidpakgkptnlsitevahglaryaaicq
anrlvpivepeiltdgshditvcaevtervlaavfkalndhhvllegallkpnmvthgsd
cpkpasheeiafytvrslkrtvppalpgvmflsggqseedaslnlnemnkmgphpfqlsf
sygralqasclkawkgvpenkakaqqvlmerarangeaql

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4tu1C (C:)
mahhhhhhmgtleaqtqgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfd
sigventeanrafyrdllfstkglgqyisgailfeetlyqkspsgvpmvdllkaegiipg
ikvdkgletlpltddekatmgldglserckkyyeagarfakwravlsidpakgkptnlsi
tevahglaryaaicqanrlvpivepeiltdgshditvcaevtervlaavfkalndhhvll
egallkpnmvthgsdcpkpasheeiafytvrslkrtvppalpgvmflsggqseedaslnl
nemnkmgphpfqlsfsygralqasclkawkgvpenkakaqqvlmerarangeaql

    Sequence, based on observed residues (ATOM records): (download) 
    >4tu1C (C:)
tqgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfdsigventeanrafyr
dllfstkglgqyisgailfeetlyqkspsgvpmvdllkaegiipgikvdkgletlpltdd
ekatmgldglserckkyyeagarfakwravlsidpakgkptnlsitevahglaryaaicq
anrlvpivepeiltdgshditvcaevtervlaavfkalndhhvllegallkpnmvthgsd
cpkpasheeiafytvrslkrtvppalpgvmflsggqseedaslnlnemnkmgphpfqlsf
sygralqasclkawkgvpenkakaqqvlmerarangeaql

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4tu1D (D:)
mahhhhhhmgtleaqtqgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfd
sigventeanrafyrdllfstkglgqyisgailfeetlyqkspsgvpmvdllkaegiipg
ikvdkgletlpltddekatmgldglserckkyyeagarfakwravlsidpakgkptnlsi
tevahglaryaaicqanrlvpivepeiltdgshditvcaevtervlaavfkalndhhvll
egallkpnmvthgsdcpkpasheeiafytvrslkrtvppalpgvmflsggqseedaslnl
nemnkmgphpfqlsfsygralqasclkawkgvpenkakaqqvlmerarangeaql

    Sequence, based on observed residues (ATOM records): (download) 
    >4tu1D (D:)
qgpgsmisqevakelaenarkiaapgkgilaadestgtikkrfdsigvenfyrdllfstk
glgqyisgailfeetlyqkspsgvpmvdllkaegiipgikvdkgletlpltddekatmgl
dglserckkyyeagarfakwravlsidpakgkptnlsitevahglaryaaicqanrlvpi
vepeiltdgshditvcaevtervlaavfkalndhhvllegallkpnmvthgsdcpkpash
eeiafytvrslkrtvppalpgvmflsggqseedaslnlnemnkmgphpfqlsfsygralq
asclkawkgvpenkakaqqvlmerarangeaql