PDB entry 4tqa
View 4tqa on RCSB PDB site
Description: Crystal Structure of a GDP-bound G13D Oncogenic Mutant of Human GTPase KRas
Class: hydrolase
Keywords: small gtpase, signal transduction, GDP binding, GTP binding, hydrolase
Deposited on
2014-06-10, released
2015-06-10
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-11-22, with a file datestamp of
2017-11-17.
Experiment type: XRAY
Resolution: 1.13 Å
R-factor: N/A
AEROSPACI score: 0.7
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: GTPase KRas
Species: Homo sapiens [TaxId:9606]
Gene: KRAS, KRAS2, RASK2
Database cross-references and differences (RAF-indexed):
- Uniprot P01116 (1-168)
- expression tag (0)
- engineered mutation (13)
Domains in SCOPe 2.07: d4tqaa1, d4tqaa2 - Chain 'B':
Compound: GTPase KRas
Species: Homo sapiens [TaxId:9606]
Gene: KRAS, KRAS2, RASK2
Database cross-references and differences (RAF-indexed):
- Uniprot P01116 (1-168)
- expression tag (0)
- engineered mutation (13)
Domains in SCOPe 2.07: d4tqab1, d4tqab2 - Heterogens: GDP, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4tqaA (A:)
gmteyklvvvgagdvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcd
lpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhke
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4tqaB (B:)
gmteyklvvvgagdvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcd
lpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhke