PDB entry 4tlk
View 4tlk on RCSB PDB site
Description: Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant
Class: transport protein
Keywords: human transthyretin, amyloid, transthyretin, mutant, TRANSPORT PROTEIN
Deposited on
2014-05-30, released
2015-10-21
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-12-09, with a file datestamp of
2015-12-04.
Experiment type: XRAY
Resolution: 1.44 Å
R-factor: N/A
AEROSPACI score: 0.51
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (76)
- engineered mutation (83)
Domains in SCOPe 2.06: d4tlka_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (76)
- engineered mutation (83)
Domains in SCOPe 2.06: d4tlkb_ - Heterogens: NA, GOL, PEG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4tlkA (A:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgippfhehapvvftandsgprrytiaallspysysttavvtnpkeh
hhhhh
Sequence, based on observed residues (ATOM records): (download)
>4tlkA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgippfhehapvvftandsgprrytiaallspysysttavvtn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4tlkB (B:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalgippfhehapvvftandsgprrytiaallspysysttavvtnpkeh
hhhhh
Sequence, based on observed residues (ATOM records): (download)
>4tlkB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgippfhehapvvftandsgprrytiaallspysysttavvtn