PDB entry 4tl4

View 4tl4 on RCSB PDB site
Description: Crystal Structure of Human Transthyretin Val30Met Mutant
Class: transport protein
Keywords: human transthyretin, amyloid, transthyretin, mutant, TRANSPORT PROTEIN
Deposited on 2014-05-29, released 2015-10-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-12-09, with a file datestamp of 2015-12-04.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (21)
    Domains in SCOPe 2.07: d4tl4a_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (21)
    Domains in SCOPe 2.07: d4tl4b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4tl4A (A:)
    kcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegi
    ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpkeh
    hhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4tl4A (A:)
    cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4tl4B (B:)
    kcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegi
    ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpkeh
    hhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4tl4B (B:)
    cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp