PDB entry 4tkw

View 4tkw on RCSB PDB site
Description: Crystal Structure of Human Transthyretin Leu55Pro Mutant
Class: transport protein
Keywords: human transthyretin, amyloid, transthyretin, mutant, TRANSPORT PROTEIN
Deposited on 2014-05-28, released 2015-10-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-12-14, with a file datestamp of 2016-12-09.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (46)
    Domains in SCOPe 2.07: d4tkwa_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02766
      • engineered mutation (46)
    Domains in SCOPe 2.07: d4tkwb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4tkwA (A:)
    kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltteeefvegi
    ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpkeh
    hhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4tkwA (A:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4tkwB (B:)
    kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltteeefvegi
    ykveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpkeh
    hhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >4tkwB (B:)
    cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgephgltteeefvegiy
    kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn