PDB entry 4s30

View 4s30 on RCSB PDB site
Description: ERK2 intrinsically active mutant (I84A)
Class: transferase
Keywords: signal transduction, phosphorylation, TRANSFERASE
Deposited on 2015-01-26, released 2016-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-01-27, with a file datestamp of 2016-01-22.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Mapk1, Erk2, Mapk, Prkm1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63086
      • engineered mutation (83)
    Domains in SCOPe 2.08: d4s30a_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4s30A (A:)
maaaaaagpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehq
tycqrtlreikillrfrheniigandiiraptieqmkdvyivqdlmetdlykllktqhls
ndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtg
flteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilg
ilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkri
eveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyrs

    Sequence, based on observed residues (ATOM records): (download) 
    >4s30A (A:)
aaaagqvfdvgprytnlsyigegagmvcsaydnlnkvrvaikkispfehqtycqrtlrei
killrfrheniigandiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyflyq
ilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvatrw
yrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedl
nciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpy
leqyydpsdepiaeapfkfdmelpkeklkelifeetarfqpg