PDB entry 4s2z

View 4s2z on RCSB PDB site
Description: ERK2 Intrinsically active mutant R65S
Class: transferase
Keywords: signal transduction, phosphorylation, kinase, TRANSFERASE
Deposited on 2015-01-25, released 2016-01-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-01-27, with a file datestamp of 2016-01-22.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Mapk1, Erk2, Mapk, Prkm1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63086
      • engineered mutation (64)
    Domains in SCOPe 2.06: d4s2za_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4s2zA (A:)
maaaaaagpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehq
tycqstlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhls
ndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtg
flteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilg
ilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkri
eveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyrs

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2zA (A:)
aaaagpqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqstlr
eikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyfl
yqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyvat
rwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqe
dlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalah
pyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqp