PDB entry 4s2k

View 4s2k on RCSB PDB site
Description: OXA-48 in complex with Avibactam at pH 7.5
Class: hydrolase/antibiotic
Keywords: inhibitor, beta-lactamase, hydrolase-antibiotic complex
Deposited on 2015-01-20, released 2015-02-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s2ka_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s2kb_
  • Chain 'C':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s2kc_
  • Chain 'D':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: bla OXA-48, blaOXA-48, FP68_27275, KPE71T_00045
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s2kd_
  • Heterogens: NXL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4s2kA (A:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2kA (A:)
ewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslialdl
gvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhafd
ygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangdy
iiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqeki
ip

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4s2kB (B:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2kB (B:)
vakewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslia
ldlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlh
afdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamltean
gdyiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkq
ekiip

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4s2kC (C:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2kC (C:)
vakewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslia
ldlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlh
afdygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamltean
gdyiiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkq
ekiip

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4s2kD (D:)
mrvlalsavflvasiigmpavakewqenkswnahftehksqgvvvlwnenkqqgftnnlk
ranqaflpastfkipnslialdlgvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvv
pvyqefarqigearmskmlhafdygnedisgnvdsfwldggirisateqisflrklyhnk
lhvsersqrivkqamlteangdyiiraktgystriepkigwwvgwvelddnvwffamnmd
mptsdglglrqaitkevlkqekiip

    Sequence, based on observed residues (ATOM records): (download) 
    >4s2kD (D:)
ewqenkswnahftehksqgvvvlwnenkqqgftnnlkranqaflpastfkipnslialdl
gvvkdehqvfkwdgqtrdiatwnrdhnlitamkysvvpvyqefarqigearmskmlhafd
ygnedisgnvdsfwldggirisateqisflrklyhnklhvsersqrivkqamlteangdy
iiraktgystriepkigwwvgwvelddnvwffamnmdmptsdglglrqaitkevlkqeki
ip