PDB entry 4s0u

View 4s0u on RCSB PDB site
Description: Crystal structure of NKG2D in complex with ULBP6
Class: immune system
Keywords: Leukaemia, Graft versus Leukaemia, c-type lectin domain, IMMUNE SYSTEM, NKG2D, NKG2DL, affinity and autoimmunity
Deposited on 2015-01-06, released 2016-04-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-06-14, with a file datestamp of 2017-06-09.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nkg2-d type II integral membrane protein
    Species: Homo sapiens [TaxId:9606]
    Gene: D12S2489E, KLRK1, NKG2D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s0ua_
  • Chain 'B':
    Compound: nkg2-d type II integral membrane protein
    Species: Homo sapiens [TaxId:9606]
    Gene: D12S2489E, KLRK1, NKG2D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4s0ub_
  • Chain 'C':
    Compound: Retinoic acid early transcript 1L protein
    Species: Homo sapiens [TaxId:9606]
    Gene: RAET1L, ULBP6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5VY80 (0-174)
      • engineered mutation (5)
    Domains in SCOPe 2.07: d4s0uc_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4s0uA (A:)
pltesycgpcpknwicyknncyqffdesknwyesqascmsqnasllkvyskedqdllklv
ksyhwmglvhiptngswqwedgsilspnlltiiemqkgdcalyassfkgyiencstpnty
icmqrt

    Sequence, based on observed residues (ATOM records): (download) 
    >4s0uA (A:)
tesycgpcpknwicyknncyqffdesknwyesqascmsqnasllkvyskedqdllklvks
yhwmglvhiptngswqwedgsilspnlltiiemqkgdcalyassfkgyiencstpntyic
mqrt

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4s0uB (B:)
pltesycgpcpknwicyknncyqffdesknwyesqascmsqnasllkvyskedqdllklv
ksyhwmglvhiptngswqwedgsilspnlltiiemqkgdcalyassfkgyiencstpnty
icmqrt

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4s0uC (C:)
dphslsyditvipkfrpgprwcavqgqvdektflhydcgnktvtpvsplgkklnvtmawk
aqnpvlrevvdilteqlldiqlenytpkepltlqarmsceqkaeghssgswqfsidgqtf
llfdsekrmwttvhpgarkmkekwendkdvamsfhyismgdcigwledflmgmds