PDB entry 4rl2

View 4rl2 on RCSB PDB site
Description: Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Class: hydrolase
Keywords: NDM-1 antibiotic hydrolysis, hydrolase
Deposited on 2014-10-15, released 2014-11-19
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-11-19, with a file datestamp of 2014-11-14.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: 0.149
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase NDM-1
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaNDM-1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4rl2a_
  • Chain 'B':
    Compound: Beta-lactamase NDM-1
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaNDM-1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4rl2b_
  • Heterogens: ZN, 3S3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rl2A (A:)
gshmgeirptigqqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdgg
rvlvvdtawtddqtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanal
snqlapqegmvaaqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdia
fggclikdskakslgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtar
madklr

    Sequence, based on observed residues (ATOM records): (download) 
    >4rl2A (A:)
eirptigqqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdggrvlvv
dtawtddqtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanalsnqla
pqegmvaaqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdiafggcl
ikdskakslgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtarmadkl
r

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4rl2B (B:)
gshmgeirptigqqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdgg
rvlvvdtawtddqtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanal
snqlapqegmvaaqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdia
fggclikdskakslgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtar
madklr

    Sequence, based on observed residues (ATOM records): (download) 
    >4rl2B (B:)
eirptigqqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdggrvlvv
dtawtddqtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanalsnqla
pqegmvaaqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdiafggcl
ikdskakslgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtarmadkl
r