PDB entry 4re5

View 4re5 on RCSB PDB site
Description: Acylaminoacyl peptidase complexed with a chloromethylketone inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: beta-propeller, alpha-beta-hydrolase fold, chloromethyl-ketone inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-09-22, released 2015-01-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acylamino-acid-releasing enzyme
    Species: Aeropyrum pernix [TaxId:272557]
    Gene: APE_1547.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4re5a1, d4re5a2
  • Chain 'B':
    Compound: Acylamino-acid-releasing enzyme
    Species: Aeropyrum pernix [TaxId:272557]
    Gene: APE_1547.1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4re5b1, d4re5b2
  • Heterogens: Y3A, ACT, MPD, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4re5A (A:)
mriimpvefsrivrdverliavekyslqgvvdgdkllvvgfsegsvnaylydggetvkln
repinsvldphygvgrvilvrdvskgaeqhalfkvntsrpgeeqrleavkpmrilsgvdt
geavvftgatedrvalyaldggglrelarlpgfgfvsdirgdliaglgffgggrvslfts
nlssgglrvfdsgegsfssasispgmkvtagletarearlvtvdprdgsvedlelpskdf
ssyrptaitwlgylpdgrlavvarregrsavfidgerveapqgnhgrvvlwrgklvtsht
slstpprivslpsgepllegglpedlrrsiagsrlvwvesfdgsrvptyvlesgraptpg
ptvvlvhggpfaedsdswdtfaaslaaagfhvvmpnyrgstgygeewrlkiigdpcggel
edvsaaarwaresglaselyimgysyggymtlcaltmkpglfkagvagasvvdweemyel
sdaafrnfieqltggsreimrsrspinhvdrikeplalihpqndsrtplkpllrlmgell
argktfeahiipdaghaintmedavkillpavfflatqrerr

    Sequence, based on observed residues (ATOM records): (download) 
    >4re5A (A:)
efsrivrdverliavekyslqgvvdgdkllvvgfsegsvnaylydggetvklnrepinsv
ldphygvgrvilvrdvskgaeqhalfkvntsrpgeeqrleavkpmrilsgvdtgeavvft
gatedrvalyaldggglrelarlpgfgfvsdirgdliaglgffgggrvslftsnlssggl
rvfdsgegsfssasispgmkvtagletarearlvtvdprdgsvedlelpskdfssyrpta
itwlgylpdgrlavvarregrsavfidgerveapqgnhgrvvlwrgklvtshtslstppr
ivslpsgepllegglpedlrrsiagsrlvwvesfdgsrvptyvlesgraptpgptvvlvh
ggpfaedsdswdtfaaslaaagfhvvmpnyrgstgygeewrlkiigdpcggeledvsaaa
rwaresglaselyimgysyggymtlcaltmkpglfkagvagasvvdweemyelsdaafrn
fieqltggsreimrsrspinhvdrikeplalihpqndsrtplkpllrlmgellargktfe
ahiipdaghaintmedavkillpavfflatqrer

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4re5B (B:)
mriimpvefsrivrdverliavekyslqgvvdgdkllvvgfsegsvnaylydggetvkln
repinsvldphygvgrvilvrdvskgaeqhalfkvntsrpgeeqrleavkpmrilsgvdt
geavvftgatedrvalyaldggglrelarlpgfgfvsdirgdliaglgffgggrvslfts
nlssgglrvfdsgegsfssasispgmkvtagletarearlvtvdprdgsvedlelpskdf
ssyrptaitwlgylpdgrlavvarregrsavfidgerveapqgnhgrvvlwrgklvtsht
slstpprivslpsgepllegglpedlrrsiagsrlvwvesfdgsrvptyvlesgraptpg
ptvvlvhggpfaedsdswdtfaaslaaagfhvvmpnyrgstgygeewrlkiigdpcggel
edvsaaarwaresglaselyimgysyggymtlcaltmkpglfkagvagasvvdweemyel
sdaafrnfieqltggsreimrsrspinhvdrikeplalihpqndsrtplkpllrlmgell
argktfeahiipdaghaintmedavkillpavfflatqrerr

    Sequence, based on observed residues (ATOM records): (download) 
    >4re5B (B:)
efsrivrdverliavekyslqgvvdgdkllvvgfsegsvnaylydggetvklnrepinsv
ldphygvgrvilvrdvskgaeqhalfkvntsrpgeeqrleavkpmrilsgvdtgeavvft
gatedrvalyaldggglrelarlpgfgfvsdirgdliaglgffgggrvslftsnlssggl
rvfdsgegsfssasispgmkvtagletarearlvtvdprdgsvedlelpskdfssyrpta
itwlgylpdgrlavvarregrsavfidgerveapqgnhgrvvlwrgklvtshtslstppr
ivslpsgepllegglpedlrrsiagsrlvwvesfdgsrvptyvlesgraptpgptvvlvh
ggpfaedsdswdtfaaslaaagfhvvmpnyrgstgygeewrlkiigdpcggeledvsaaa
rwaresglaselyimgysyggymtlcaltmkpglfkagvagasvvdweemyelsdaafrn
fieqltggsreimrsrspinhvdrikeplalihpqndsrtplkpllrlmgellargktfe
ahiipdaghaintmedavkillpavfflatqrer