PDB entry 4rdd

View 4rdd on RCSB PDB site
Description: Co-crystal structure of SHP2 in complex with a Cefsulodin derivative
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2014-09-18, released 2015-07-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-07-01, with a file datestamp of 2015-06-26.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 11
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN11, PTP2C, SHPTP2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4rdda_
  • Heterogens: 3LU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rddA (A:)
lysrkegqrqenknknryknilpfdhtrvvlhdgdpnepvsdyinaniimpefetkcnns
kpkksyiatqgclqntvndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeyg
vmrvrnvkesaahdytlrelklskvgqgntertvwqyhfrtwpdhgvpsdpggvldflee
vhhkqesimdagpvvvhcsagigrtgtfividilidiirekgvdcdidvpktiqmvrsqr
sgmvqteaqyrfiymavqhyietlqrrlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4rddA (A:)
lysrkegqrqenknknryknilpfdhtrvvlhdgdpnepvsdyinaniimpefetkcnns
kpkksyiatqgclqntvndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeyg
vmrvrnvkesaahdytlrelklskvgqgntertvwqyhfrtwpdhgvpsdpggvldflee
vhhkqesimdagpvvvhcsagigrtgtfividilidiirekgvdcdidvpktiqmvrsqr
sgmvqteaqyrfiymavqhyietlqrr