PDB entry 4rc2

View 4rc2 on RCSB PDB site
Description: Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives
Class: Signaling protein
Keywords: kinase, phosphorylation, Signaling protein
Deposited on 2014-09-14, released 2015-03-18
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-03-18, with a file datestamp of 2015-03-13.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4rc2a_
  • Heterogens: 3O8

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rc2A (A:)
gphmkekeplesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngt
rvpmevvllkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeela
rsffwqvleavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgt
rvysppewiryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecq
hlirwclalrpsdrptfeeiqnhpwmqdvllpqetaeihlhslspgpsk

    Sequence, based on observed residues (ATOM records): (download) 
    >4rc2A (A:)
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
iryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcla
lrpsdrptfeeiqnhpwmqdvllpqetaeihlh