PDB entry 4r5a

View 4r5a on RCSB PDB site
Description: A Carbonic Anhydrase IX Mimic in Complex with a Carbohydrate-Based Sulfamate
Class: lyase
Keywords: Carbonic Anhydrase IX Mimic, LYASE
Deposited on 2014-08-20, released 2014-10-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (0-259)
      • engineered mutation (64)
      • engineered mutation (66)
      • engineered mutation (68)
      • engineered mutation (90)
      • engineered mutation (129)
      • engineered mutation (168)
      • engineered mutation (202)
    Domains in SCOPe 2.08: d4r5aa_
  • Heterogens: ZN, GOL, 3J4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r5aA (A:)
mshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghsfqvtfddsqdkavlkggpldgtyrllqfhfhwgsldgqgsehtvdkkkyaaelhl
vhwntkygdvgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktegksadftnfdp
rgllpesldywtypgslttpplaecvtwivlkepisvsseqvlkfrklnfngegepeelm
vdnwrpaqplknrqikasfk