PDB entry 4r4b

View 4r4b on RCSB PDB site
Description: Crystal structure of the anti-hiv-1 antibody 2.2c
Class: immune system
Keywords: igg, fab, hiv, immunoglobulin domain, immune system
Deposited on 2014-08-19, released 2014-09-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fab 2.2c light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-209)
    Domains in SCOPe 2.08: d4r4ba1, d4r4ba2
  • Chain 'B':
    Compound: fab 2.2c heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-219)
    Domains in SCOPe 2.08: d4r4bb1, d4r4bb2
  • Chain 'C':
    Compound: fab 2.2c light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-209)
    Domains in SCOPe 2.08: d4r4bc1, d4r4bc2
  • Chain 'D':
    Compound: fab 2.2c heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-219)
    Domains in SCOPe 2.08: d4r4bd1, d4r4bd2
  • Chain 'E':
    Compound: fab 2.2c light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-209)
    Domains in SCOPe 2.08: d4r4be1, d4r4be2
  • Chain 'F':
    Compound: fab 2.2c heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-219)
    Domains in SCOPe 2.08: d4r4bf1, d4r4bf2
  • Chain 'H':
    Compound: fab 2.2c heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-219)
    Domains in SCOPe 2.08: d4r4bh1, d4r4bh2
  • Chain 'L':
    Compound: fab 2.2c light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4R4B (0-209)
    Domains in SCOPe 2.08: d4r4bl1, d4r4bl2
  • Heterogens: SO4, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r4bA (A:)
diqmtqspsfvsasvgdrvtitcrasqgissylawyqqkpgkapklviyaastlqsgvps
rfsgsgsgteftltisslqpedfatyycqhliglrsfgqgtkleikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r4bB (B:)
qvqlqqwgagllkpsetlsltcgvygeslsghywswvrqppgkrlewigeikhngspnyh
pslksrvtisldmsknqfslnltsvtaadtavyfcarrsnwpylpfdpwgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4r4bC (C:)
diqmtqspsfvsasvgdrvtitcrasqgissylawyqqkpgkapklviyaastlqsgvps
rfsgsgsgteftltisslqpedfatyycqhliglrsfgqgtkleikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnr

    Sequence, based on observed residues (ATOM records): (download) 
    >4r4bC (C:)
diqmtqspsfvsasvgdrvtitcrasqgissylawyqqkpgkapklviyaastlrfsgsg
sgteftltisslqpedfatyycqhliglrsfgqgtkleikrtvaapsvfifppsdeqlks
gtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskadye
khkvyacevthqglsspvtksfnr

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r4bD (D:)
qvqlqqwgagllkpsetlsltcgvygeslsghywswvrqppgkrlewigeikhngspnyh
pslksrvtisldmsknqfslnltsvtaadtavyfcarrsnwpylpfdpwgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4r4bE (E:)
diqmtqspsfvsasvgdrvtitcrasqgissylawyqqkpgkapklviyaastlqsgvps
rfsgsgsgteftltisslqpedfatyycqhliglrsfgqgtkleikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnr

    Sequence, based on observed residues (ATOM records): (download) 
    >4r4bE (E:)
diqmtqspsfvsasvgdrvtitcrasqgissylawyqqkpgkapklviyaastlrfsgsg
sgteftltisslqpedfatyycqhliglrsfgqgtkleikrtvaapsvfifppsdeqlks
gtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltlskadye
khkvyacevthqglsspvtksfnr

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r4bF (F:)
qvqlqqwgagllkpsetlsltcgvygeslsghywswvrqppgkrlewigeikhngspnyh
pslksrvtisldmsknqfslnltsvtaadtavyfcarrsnwpylpfdpwgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r4bH (H:)
qvqlqqwgagllkpsetlsltcgvygeslsghywswvrqppgkrlewigeikhngspnyh
pslksrvtisldmsknqfslnltsvtaadtavyfcarrsnwpylpfdpwgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4r4bL (L:)
diqmtqspsfvsasvgdrvtitcrasqgissylawyqqkpgkapklviyaastlqsgvps
rfsgsgsgteftltisslqpedfatyycqhliglrsfgqgtkleikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnr