PDB entry 4r21

View 4r21 on RCSB PDB site
Description: Zebra fish cytochrome P450 17A2 with Progesterone
Class: oxidoreductase
Keywords: Cytochrome P450 17A2, progesterone, P450 17A2, 17 (alpha)-hydroxylation, steroid biosynthesis, enzyme kinetics, OXIDOREDUCTASE
Deposited on 2014-08-08, released 2014-12-31
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-03-04, with a file datestamp of 2015-02-27.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 family 17 polypeptide 2
    Species: Danio rerio [TaxId:7955]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4r21a_
  • Chain 'B':
    Compound: Cytochrome P450 family 17 polypeptide 2
    Species: Danio rerio [TaxId:7955]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4r21b_
  • Heterogens: HEM, STR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4r21A (A:)
makktsskgkegvgsssvsfpclprlpllgsllhlrsnlpphllftqlssqygplfglya
gphltlvvseiglvrevllqrgrefagrpkmvttdlltqggkdiafadysplwknhrrlv
hssftlfgegsnklqtivqeaadslceelqacrgqssdlsvvlmravtnvicrlvfsssy
qpsdpelqtviqyndgivqtiargglvdifpwlrifpnkdlkrlkecvsirdqllykkll
ehkksltpgeprdlldalligqqrgsggadditedhvlmtaaeafgagvettsttllwti
afllhhpqlqervqaeldecvgvdrppclsdrphlplldavlcevmrirpvspiliphva
mqdtslgghsvpkgtrvlvnmwaihhdpkhwdqpeqfnperflepsgkkktqssflpfga
gprvcvgeslarielflfvsrplqrfsfscpseaslpdlqgrfgvvlqperytvtvtprh
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4r21A (A:)
nlpphllftqlssqygplfglyagphltlvvseiglvrevllqrgrefagrpkmvttdll
tqggkdiafadysplwknhrrlvhssftlfgegsnklqtivqeaadslceelqacrgqss
dlsvvlmravtnvicrlvfsssyqpsdpelqtviqyndgivqtiargglvdikdlkrlke
cvsirdqllykkllehkksltpgeprdlldalligqqrgsggadditedhvlmtaaeafg
agvettsttllwtiafllhhpqlqervqaeldecvgvdrppclsdrphlplldavlcevm
rirpvspiliphvamqdtslgghsvpkgtrvlvnmwaihhdpkhwdqpeqfnperfless
flpfgagprvcvgeslarielflfvsrplqrfsfscpslpdlqgrfgvvlqperytvtvt
pr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4r21B (B:)
makktsskgkegvgsssvsfpclprlpllgsllhlrsnlpphllftqlssqygplfglya
gphltlvvseiglvrevllqrgrefagrpkmvttdlltqggkdiafadysplwknhrrlv
hssftlfgegsnklqtivqeaadslceelqacrgqssdlsvvlmravtnvicrlvfsssy
qpsdpelqtviqyndgivqtiargglvdifpwlrifpnkdlkrlkecvsirdqllykkll
ehkksltpgeprdlldalligqqrgsggadditedhvlmtaaeafgagvettsttllwti
afllhhpqlqervqaeldecvgvdrppclsdrphlplldavlcevmrirpvspiliphva
mqdtslgghsvpkgtrvlvnmwaihhdpkhwdqpeqfnperflepsgkkktqssflpfga
gprvcvgeslarielflfvsrplqrfsfscpseaslpdlqgrfgvvlqperytvtvtprh
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4r21B (B:)
nlpphllftqlssqygplfglyagphltlvvseiglvrevllqrgrefagrpkmvttdll
tqggkdiafadysplwknhrrlvhssftlfgegsnklqtivqeaadslceelqacrgqss
dlsvvlmravtnvicrlvfsssyqpsdpelqtviqyndgivqtiarggnkdlkrlkecvs
irdqllykkllehkksltpgeprdlldalligqqrgsggadditedhvlmtaaeafgagv
ettsttllwtiafllhhpqlqervqaeldecvgvdrppclsdrphlplldavlcevmrir
pvspiliphvamqdtslgghsvpkgtrvlvnmwaihhdpkhwdqpeqfnperflepqssf
lpfgagprvcvgeslarielflfvsrplqrfsfscpseaslpdlqgrfgvvlqperytvt
vtp