PDB entry 4qr5

View 4qr5 on RCSB PDB site
Description: Brd4 Bromodomain 1 complex with its novel inhibitors
Class: transcription/transcription inhibitor
Keywords: BRD4, Bromodomain, four alpha helices, TRANSCRIPTION-TRANSCRIPTION INHIBITOR complex
Deposited on 2014-06-30, released 2015-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-07-01, with a file datestamp of 2015-06-26.
Experiment type: XRAY
Resolution: 1.41 Å
R-factor: N/A
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-124)
    • expression tag (0-1)
  Domains in SCOPe 2.08: d4qr5a1, d4qr5a2
• Heterogens: BNM, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4qr5A (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelpt