PDB entry 4qpl

View 4qpl on RCSB PDB site
Description: Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex
Class: ligase
Keywords: Protein poly(ADP-ribosy)lation, ubiquitination, E2/E3 ubiquitin ligase, Wnt signaling, RNF146, UbcH5a, iso-ADPR, LIGASE
Deposited on 2014-06-23, released 2014-10-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase RNF146
    Species: Mus musculus [TaxId:10090]
    Gene: RNF146
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ubiquitin-conjugating enzyme e2 d1
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2D1, SFT, UBC5A, UBCH5, UBCH5A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51668 (7-153)
      • expression tag (5-6)
    Domains in SCOPe 2.08: d4qplb1, d4qplb2
  • Chain 'C':
    Compound: E3 ubiquitin-protein ligase RNF146
    Species: Mus musculus [TaxId:10090]
    Gene: RNF146
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ubiquitin-conjugating enzyme e2 d1
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2D1, SFT, UBC5A, UBCH5, UBCH5A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51668 (7-153)
      • expression tag (1-6)
    Domains in SCOPe 2.08: d4qpld1, d4qpld2
  • Heterogens: V3L, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4qplB (B:)
hhhhhhamalkriqkelsdlqrdppahcsagpvgddlfhwqatimgppdsayqggvfflt
vhfptdypfkppkiafttkiyhpninsngsicldilrsqwspaltvskvllsicsllcdp
npddplvpdiaqiyksdkekynrharewtqkyam

    Sequence, based on observed residues (ATOM records): (download) 
    >4qplB (B:)
hamalkriqkelsdlqrdppahcsagpvgddlfhwqatimgppdsayqggvffltvhfpt
dypfkppkiafttkiyhpninsngsicldilrsqwspaltvskvllsicsllcdpnpddp
lvpdiaqiyksdkekynrharewtqkyam

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4qplD (D:)
hhhhhhamalkriqkelsdlqrdppahcsagpvgddlfhwqatimgppdsayqggvfflt
vhfptdypfkppkiafttkiyhpninsngsicldilrsqwspaltvskvllsicsllcdp
npddplvpdiaqiyksdkekynrharewtqkyam

    Sequence, based on observed residues (ATOM records): (download) 
    >4qplD (D:)
hhhhhamalkriqkelsdlqrdppahcsagpvgddlfhwqatimgppdsayqggvffltv
hfptdypfkppkiafttkiyhpninsngsicldilrsqwspaltvskvllsicsllcdpn
pddplvpdiaqiyksdkekynrharewtqkyam