PDB entry 4qnp

View 4qnp on RCSB PDB site
Description: Crystal structure of the 2009 pandemic H1N1 influenza virus neuraminidase with a neutralizing antibody
Class: hydrolase/immune system
Keywords: influenza, neuraminidase, antibody, neutralizing antibody, HYDROLASE-IMMUNE SYSTEM complex
Deposited on 2014-06-18, released 2015-02-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-02-25, with a file datestamp of 2015-02-20.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.183
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:11320]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4qnpa_
  • Chain 'B':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:11320]
    Gene: NA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4qnpb_
  • Chain 'E':
    Compound: neutralizing antibody, heavy chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4QNP (0-223)
  • Chain 'F':
    Compound: neutralizing antibody, light chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4QNP (0-211)
    Domains in SCOPe 2.07: d4qnpf1, d4qnpf2
  • Chain 'H':
    Compound: neutralizing antibody, heavy chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4QNP (0-223)
  • Chain 'L':
    Compound: neutralizing antibody, light chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 4QNP (0-End)
    Domains in SCOPe 2.07: d4qnpl1, d4qnpl2
  • Heterogens: NAG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4qnpA (A:)
    svklagnsslcpvsgwaiyskdnsvrigskgdvfvirepfiscsplecrtffltqgalln
    dkhsngtikdrspyrtlmscpigevpspynsrfesvawsasachdginwltigisgpdng
    avavlkyngiitdtikswrnnilrtqesecacvngscftvmtdgpsngqasykifriekg
    kivksvemnapnyhyeecscypdsseitcvcrdnwhgsnrpwvsfnqnleyqigyicsgi
    fgdnprpndktgscgpvssngangvkgfsfkygngvwigrtksissrngfemiwdpngwt
    gtdnnfsikqdivginewsgysgsfvqhpeltgldcirpcfwvelirgrpkentiwtsgs
    sisfcgvnsdtvgwswpdgaelpfti
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4qnpB (B:)
    svklagnsslcpvsgwaiyskdnsvrigskgdvfvirepfiscsplecrtffltqgalln
    dkhsngtikdrspyrtlmscpigevpspynsrfesvawsasachdginwltigisgpdng
    avavlkyngiitdtikswrnnilrtqesecacvngscftvmtdgpsngqasykifriekg
    kivksvemnapnyhyeecscypdsseitcvcrdnwhgsnrpwvsfnqnleyqigyicsgi
    fgdnprpndktgscgpvssngangvkgfsfkygngvwigrtksissrngfemiwdpngwt
    gtdnnfsikqdivginewsgysgsfvqhpeltgldcirpcfwvelirgrpkentiwtsgs
    sisfcgvnsdtvgwswpdgaelpfti
    

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4qnpF (F:)
    qivlsqspailsaspgekvtmtcrtsssvsymhwyqqkpgsspkpwiyatsnlasgvpfr
    fsgsgsgtsysltisrveaedaatyycqqwnsnpptfgggtkleikradaaptvsifpps
    seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
    tkdeyerhnsytceathktstspivksfnrne
    

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >4qnpL (L:)
    qivlsqspailsaspgekvtmtcrtsssvsymhwyqqkpgsspkpwiyatsnlasgvpfr
    fsgsgsgtsysltisrveaedaatyycqqwnsnpptfgggtkleikradaaptvsifpps
    seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
    tkdeyerhnsytceathktstspivksfnrne
    

    Sequence, based on observed residues (ATOM records): (download)
    >4qnpL (L:)
    qivlsqspailsaspgekvtmtcrtsssvsymhwyqqkpgsspkpwiyatsnlasgvpfr
    fsgsgsgtsysltisrveaedaatyycqqwnsnpptfgggtkleikradaaptvsifpps
    seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
    tkdeyerhnsytceathktstspivksfnrn