PDB entry 4qmu

View 4qmu on RCSB PDB site
Description: mst3 in complex with jnj-7706621, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide
Class: Transferase/transferase inhibitor
Keywords: PROTEIN KINASE, MST3, STK24, STERILE 20-LIKE KINASE, ATP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-TRANSFERASE, Transferase-transferase inhibitor complex
Deposited on 2014-06-16, released 2015-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-07-13, with a file datestamp of 2016-07-08.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase 24
    Species: Homo sapiens [TaxId:9606]
    Gene: STK24, MST3, STK3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4qmua_
  • Heterogens: SKE, MG, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qmuA (A:)
gplgsefmahspvqsglpgmqnlkadpeelftklekigkgsfgevfkgidnrtqkvvaik
iidleeaedeiediqqeitvlsqcdspyvtkyygsylkdtklwiimeylgggsaldllep
gpldetqiatilreilkgldylhsekkihrdikaanvllsehgevkladfgvagqltdtq
ikrntfvgtpfwmapevikqsaydskadiwslgitaielargepphselhpmkvlflipk
nnpptlegnyskplkefveaclnkepsfrptakellkhkfilrnakktsyltelidrykr
wkaeqshdds

    Sequence, based on observed residues (ATOM records): (download) 
    >4qmuA (A:)
gmqnlkadpeelftklekigkgsfgevfkgidnrtqkvvaikiidleeaedeiediqqei
tvlsqcdspyvtkyygsylkdtklwiimeylgggsaldllepgpldetqiatilreilkg
ldylhsekkihrdikaanvllsehgevkladfgvagqltdtqikrntfvgtpfwmapevi
kqsaydskadiwslgitaielargepphselhpmkvlflipknnpptlegnyskplkefv
eaclnkepsfrptakellkhkfilrnakktsyltelidrykrwkaeq