PDB entry 4qlf
View 4qlf on RCSB PDB site
Description: Crystal structure of I14G DHFR mutant complexed with folate and NADP+
Class: oxidoreductase
Keywords: dihydrofolate-reductase like fold/Alpha and beta proteins (a/b), oxidoreductase activity, NADP(H) binding, oxidoreductase
Deposited on
2014-06-12, released
2014-11-26
The last revision prior to the SCOPe 2.08 freeze date was dated
2015-02-25, with a file datestamp of
2015-02-20.
Experiment type: XRAY
Resolution: 1.44 Å
R-factor: 0.183
AEROSPACI score: 0.57
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:1403831]
Gene: folA, BN896_0046
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4qlfa_ - Heterogens: FOL, NAP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4qlfA (A:)
misliaalavdrvggmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr
Sequence, based on observed residues (ATOM records): (download)
>4qlfA (A:)
misliaalavdrvggmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
ghfpdyepddwesvfsefhdadaqnshsycfeilerr