PDB entry 4qir

View 4qir on RCSB PDB site
Description: Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-2-(pyridin-3-yl)ethylGlyP[CH2]Phe
Class: hydrolase
Keywords: alanine aminopeptidase, Aminopeptidase N, M1 family peptidases, 3-{[(R)-1-amino-3-(pyridin-3-yl)propyl](hydroxy)phosphoryl}-(S)-2-benzylpropanoic acid, HYDROLASE
Deposited on 2014-06-01, released 2014-09-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-10-22, with a file datestamp of 2014-10-17.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.151
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aminopeptidase N
    Species: Neisseria meningitidis MC58 [TaxId:122586]
    Gene: pepN, NMB1416
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4qira1, d4qira2, d4qira3, d4qira4
  • Heterogens: 379, GOL, IMD, ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4qirA (A:)
snamsktvhylkdyqtpayhilktdlhfdinepqtvvksrltvepqrvgeplvldgsakl
lsvkingaaadyvlegetltiagvpserftveveteilpaenkslmglyasggnlftqce
pegfrkitfyidrpdvmskftttivadkkrypvllsngnkidggefsdgrhwvkwedpfs
kpsylfalvagdlavtedyfttmsgrnvkiefytteadkpkvgfaveslknamkwdetrf
gleydldifmvvavgdfnmgamenkglnifntkfvladsrtatdtdfegiesvvgheyfh
nwtgnrvtcrdwfqlslkegltvfrdqefsgdrasravrrienirllrqhqfpedagpta
hpvrpasyeemnnfytmtvyekgaevvrmyhtllgeegfqkgmklyfqrhdgqavtcddf
raamadanginldqfalwysqagtpvleaegrlknnifeltvkqtvpptpdmtdkqpmmi
pvkvgllnrngeavafdyqgkrateavlllteaeqtfllegvteavvpsllrgfsapvhl
nypysdddlllllahdsdaftrweaaqtlyrravaanlatlsdgvelpkhekllaavekv
isddlldnafkalllgvpseaelwdgaenidplryhqarealldtlavhflpkwhelnrq
aakqenqsyeyspeaagwrtlrnvcrafvlradpahietvaekygemaqnmthewgilsa
vngnesdtrnrllaqfadkfsddalvmdkyfalvgssrrsdtlqqvrtalqhpkfslenp
nkarsligsfsrnvphfhaedgsgyrfiadkvieidrfnpqvaarlvqafnlcnklephr
knlvkqalqriraqeglskdvgeivgkild

    Sequence, based on observed residues (ATOM records): (download) 
    >4qirA (A:)
tvhylkdyqtpayhilktdlhfdinepqtvvksrltvepqrvgeplvldgsakllsvkin
gaaadyvlegetltiagvpserftveveteilpaenkslmglyasggnlftqcepegfrk
itfyidrpdvmskftttivadkkrypvllsngnkidggefsdgrhwvkwedpfskpsylf
alvagdlavtedyfttmsgrnvkiefytteadkpkvgfaveslknamkwdetrfgleydl
difmvvavgdfnmgamenkglnifntkfvladsrtatdtdfegiesvvgheyfhnwtgnr
vtcrdwfqlslkegltvfrdqefsgdrasravrrienirllrqhqfpedagptahpvrpa
syeemnnfytmtvyekgaevvrmyhtllgeegfqkgmklyfqrhdgqavtcddfraamad
anginldqfalwysqagtpvleaegrlknnifeltvkqtvpptpdmtdkqpmmipvkvgl
lnrngeavafdyqgkrateavlllteaeqtfllegvteavvpsllrgfsapvhlnypysd
ddlllllahdsdaftrweaaqtlyrravaanlatlsdgvelpkhekllaavekvisddll
dnafkalllgvpseaelwdgaenidplryhqarealldtlavhflpkwhelnrqaakqen
qsyeyspeaagwrtlrnvcrafvlradpahietvaekygemaqnmthewgilsavngnes
dtrnrllaqfadkfsddalvmdkyfalvgssrrsdtlqqvrtalqhpkfslenpnkarsl
igsfsrnvphfhaedgsgyrfiadkvieidrfnpqvaarlvqafnlcnklephrknlvkq
alqriraqeglskdvgeivgkild