SCOPe 2.08: Structural Classification of Proteins

PDB entry 4qii

View 4qii on RCSB PDB site
Description: Crystal Structure of type II MenB from Mycobacteria tuberculosis
Class: lyase
Keywords: 1,4-dihydroxy-2-naphthoyl-coenzyme A, synthase, LYASE
Deposited on 2014-05-31, released 2014-11-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-11-19, with a file datestamp of 2014-11-14.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: 0.152
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiia_
Chain 'B':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiib_
Chain 'C':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiic_
Chain 'D':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiid_
Chain 'E':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiie_
Chain 'F':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiif_
Chain 'G':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiig_
Chain 'H':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiih_
Chain 'I':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiii_
Chain 'J':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiij_
Chain 'K':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiik_
Chain 'L':
Compound: 1,4-Dihydroxy-2-naphthoyl-CoA synthase
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
- Uniprot P9WNP5 (Start-333)
Domains in SCOPe 2.08: d4qiil_
Heterogens: 2NE, PGE, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>4qiiA (A:)
mgsshhhhhhssglvprgshmvapageqgrsstalsdnpfdakawrlvdgfddltdityh
rhvddatvrvafnrpevrnafrphtvdelyrvldharmspdvgvvlltgngpspkdggwa
fcsggdqrirgrsgyqyasgdtadtvdvaragrlhilevqrlirfmpkvviclvngwaag
gghslhvvcdltlasreyarfkqtdadvgsfdggygsaylarqvgqkfareifflgrtyt
aeqmhqmgavnavaehaeletvglqwaaeinakspqaqrmlkfafnllddglvgqqlfag
eatrlaymtdeavegrdaflqkrppdwspfpryf